A decade or so ago, filler was often injected into the nasolabial folds, or laugh lines, to literally fill the wrinkles themselves. These days, the goal is to plump and lift in other parts of the face for a more natural-looking result. “As you age, your bones get thinner, and the overlying fat pads slide down,” which makes the skin sag lower, causing deeper folds at the bottoms of your cheeks, Whitney Bowe, M.D., a dermatologist in New York City, tells SELF. Bowe often injects Restylane Lyft right near the cheekbone to restore fullness, which lifts the face, reducing the look of smile lines in the process.5. It matters who does your filler.